The concert party is free and open to the general public, with all club cover charges waived for this special event.
Internext badge holders and their guests will have exclusive access to the Cabana and Skybox levels of Rain. The group should hit the stage around 11 p.m.
Seinfeld's latest band made its debut in March 2007. The Spyderz also features bassist John Monte, formerly of Ministry and M.O.D., lead guitarist Dirrty, and drummer Lee Nelson.
Seinfeld is also an adult film star, performing under the name Spyder Jonz. His mainstream acting career includes a six-year run on the HBO prison drama Oz.